P44T (p.Pro44Thr) variant of HLA-C (P10321)
P44T (p.Pro44Thr) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
P44T (p.Pro44Thr) variant details
- p.Pro44Thr
- ExAC rs780748676
- Missense
- Variant Prioritization Score for Impact Estimate 0.281
- REVEL 0.11
- CADD 22.70
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available