P39L (p.Pro39Leu) variant of HLA-C (P10321)
P39L (p.Pro39Leu) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
P39L (p.Pro39Leu) variant details
- p.Pro39Leu
- ExAC rs281860335
- gnomAD rs281860335
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.14
- CADD 26.50
- PolyPhen-2 0.91
- SIFT 0.00
- Population evidence available
- Structural context available