M4T (p.Met4Thr) variant of HLA-C (P10321)
M4T (p.Met4Thr) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
M4T (p.Met4Thr) variant details
- p.Met4Thr
- ExAC rs199783871
- gnomAD rs199783871
- Missense
- Variant Prioritization Score for Impact Estimate 0.264
- REVEL 0.23
- CADD 1.69
- PolyPhen-2 0.00
- SIFT 0.17
- Most common in the Middle Eastern population (allele frequency 0.00035)
- Structural context available