M4K (p.Met4Lys) variant of HLA-C (P10321)
M4K (p.Met4Lys) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
M4K (p.Met4Lys) variant details
- p.Met4Lys
- ExAC rs199783871
- gnomAD rs199783871
- Missense
- Variant Prioritization Score for Impact Estimate 0.254
- REVEL 0.17
- CADD 9.21
- PolyPhen-2 0.06
- SIFT 0.03
- Most common in the 1KG:KHV population (allele frequency 0.0079)
- Structural context available