M29V (p.Met29Val) variant of HLA-C (P10321)
M29V (p.Met29Val) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
M29V (p.Met29Val) variant details
- p.Met29Val
- ExAC rs281860322
- gnomAD rs281860322
- Missense
- Variant Prioritization Score for Impact Estimate 0.122
- REVEL 0.16
- CADD 2.36
- PolyPhen-2 0.08
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 2.2e-06)
- Structural context available