M29R (p.Met29Arg) variant of HLA-C (P10321)
M29R (p.Met29Arg) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
M29R (p.Met29Arg) variant details
- p.Met29Arg
- 1000Genomes rs61759936
- ExAC rs61759936
- gnomAD rs61759936
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.16
- CADD 22.90
- PolyPhen-2 0.43
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 0.00027)
- Structural context available