M29K (p.Met29Lys) variant of HLA-C (P10321)
M29K (p.Met29Lys) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
M29K (p.Met29Lys) variant details
- p.Met29Lys
- 1000Genomes rs61759936
- ExAC rs61759936
- gnomAD rs61759936
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.17
- CADD 22.70
- PolyPhen-2 0.28
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 8.4e-05)
- Structural context available