L9P (p.Leu9Pro) variant of HLA-C (P10321)
L9P (p.Leu9Pro) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
L9P (p.Leu9Pro) variant details
- p.Leu9Pro
- Ensembl rs1761430961
- Missense
- Variant Prioritization Score for Impact Estimate 0.31
- REVEL 0.17
- CADD 24.00
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the South Asian population (allele frequency 3.4e-05)
- Structural context available