L9F (p.Leu9Phe) variant of HLA-C (P10321)
L9F (p.Leu9Phe) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
L9F (p.Leu9Phe) variant details
- p.Leu9Phe
- ExAC rs751484302
- gnomAD rs751484302
- Missense
- Variant Prioritization Score for Impact Estimate 0.273
- REVEL 0.07
- CADD 20.80
- PolyPhen-2 1.00
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 1.4e-06)
- Structural context available