L17R (p.Leu17Arg) variant of HLA-C (P10321)
L17R (p.Leu17Arg) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
L17R (p.Leu17Arg) variant details
- p.Leu17Arg
- ExAC rs774915913
- gnomAD rs774915913
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- REVEL 0.17
- CADD 24.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available