L10V (p.Leu10Val) variant of HLA-C (P10321)
L10V (p.Leu10Val) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
L10V (p.Leu10Val) variant details
- p.Leu10Val
- 1000Genomes rs2308527
- ESP rs2308527
- ExAC rs2308527
- gnomAD rs2308527
- Missense
- Variant Prioritization Score for Impact Estimate 0.183
- REVEL 0.18
- CADD 18.30
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 4.2e-05)
- Structural context available