H27P (p.His27Pro) variant of HLA-C (P10321)
H27P (p.His27Pro) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
H27P (p.His27Pro) variant details
- p.His27Pro
- Ensembl rs281860320
- Missense
- Variant Prioritization Score for Impact Estimate 0.315
- REVEL 0.19
- CADD 25.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 3.6e-05)
- Structural context available