H27L (p.His27Leu) variant of HLA-C (P10321)
H27L (p.His27Leu) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
H27L (p.His27Leu) variant details
- p.His27Leu
- Ensembl rs281860320
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.17
- CADD 25.20
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available