G42E (p.Gly42Glu) variant of HLA-C (P10321)
G42E (p.Gly42Glu) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
G42E (p.Gly42Glu) variant details
- p.Gly42Glu
- ExAC rs45574634
- Missense
- Variant Prioritization Score for Impact Estimate 0.168
- REVEL 0.14
- CADD 19.60
- PolyPhen-2 0.05
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available