G16V (p.Gly16Val) variant of HLA-C (P10321)
G16V (p.Gly16Val) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
G16V (p.Gly16Val) variant details
- p.Gly16Val
- 1000Genomes rs1050451
- ESP rs1050451
- ExAC rs1050451
- gnomAD rs1050451
- Missense
- Variant Prioritization Score for Impact Estimate 0.213
- REVEL 0.25
- CADD 13.70
- PolyPhen-2 0.00
- SIFT 0.13
- Most common in the Latino/Admixed American population (allele frequency 4e-05)
- Structural context available