G16S (p.Gly16Ser) variant of HLA-C (P10321)
G16S (p.Gly16Ser) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
G16S (p.Gly16Ser) variant details
- p.Gly16Ser
- gnomAD rs1206082893
- Missense
- Variant Prioritization Score for Impact Estimate 0.287
- REVEL 0.14
- CADD 17.40
- PolyPhen-2 0.04
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.4e-06)
- Structural context available