F46I (p.Phe46Ile) variant of HLA-C (P10321)
F46I (p.Phe46Ile) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
F46I (p.Phe46Ile) variant details
- p.Phe46Ile
- ExAC rs281860341
- gnomAD rs281860341
- Missense
- Variant Prioritization Score for Impact Estimate 0.282
- REVEL 0.15
- CADD 23.00
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available