F32V (p.Phe32Val) variant of HLA-C (P10321)
F32V (p.Phe32Val) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
F32V (p.Phe32Val) variant details
- p.Phe32Val
- gnomAD rs281860328
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.12
- CADD 23.90
- PolyPhen-2 0.83
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.1e-06)
- Structural context available