F32L (p.Phe32Leu) variant of HLA-C (P10321)
F32L (p.Phe32Leu) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
F32L (p.Phe32Leu) variant details
- p.Phe32Leu
- Ensembl rs281860329
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.12
- CADD 22.70
- PolyPhen-2 0.09
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 2.2e-06)
- Structural context available