F32I (p.Phe32Ile) variant of HLA-C (P10321)
F32I (p.Phe32Ile) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
F32I (p.Phe32Ile) variant details
- p.Phe32Ile
- gnomAD rs281860328
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.10
- CADD 23.60
- PolyPhen-2 0.69
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.1e-06)
- Structural context available