D33A (p.Asp33Ala) variant of HLA-C (P10321)
D33A (p.Asp33Ala) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
D33A (p.Asp33Ala) variant details
- p.Asp33Ala
- cosmic curated COSV66111
- 1000Genomes rs1071650
- ExAC rs1071650
- gnomAD rs1071650
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.22
- CADD 2.08
- PolyPhen-2 0.41
- SIFT 0.33
- Most common in the HGDP:OROQEN population (allele frequency 0.12)
- Structural context available