C25Y (p.Cys25Tyr) variant of HLA-C (P10321)
C25Y (p.Cys25Tyr) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
C25Y (p.Cys25Tyr) variant details
- p.Cys25Tyr
- gnomAD rs281860318
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.12
- CADD 24.70
- PolyPhen-2 0.51
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.1e-06)
- Structural context available