C25S (p.Cys25Ser) variant of HLA-C (P10321)
C25S (p.Cys25Ser) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
C25S (p.Cys25Ser) variant details
- p.Cys25Ser
- gnomAD rs281860318
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.25
- CADD 23.50
- PolyPhen-2 0.00
- SIFT 0.04
- Population evidence available
- Structural context available