A8D (p.Ala8Asp) variant of HLA-C (P10321)
A8D (p.Ala8Asp) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
A8D (p.Ala8Asp) variant details
- p.Ala8Asp
- ExAC rs755610458
- TOPMed rs755610458
- gnomAD rs755610458
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.18
- CADD 19.70
- PolyPhen-2 0.08
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00063)
- Structural context available