Y33S (p.Tyr33Ser) variant of HLA-B (P01889)
Y33S (p.Tyr33Ser) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
Y33S (p.Tyr33Ser) variant details
- p.Tyr33Ser
- ExAC rs77234140
- gnomAD rs77234140
- Missense
- Variant Prioritization Score for Impact Estimate 0.232
- REVEL 0.32
- CADD 6.31
- PolyPhen-2 0.01
- SIFT 0.54
- Most common in the South Asian population (allele frequency 0.0014)
- Structural context available