Y33F (p.Tyr33Phe) variant of HLA-B (P01889)
Y33F (p.Tyr33Phe) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
Y33F (p.Tyr33Phe) variant details
- p.Tyr33Phe
- ExAC rs77234140
- gnomAD rs77234140
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.23
- CADD 6.13
- PolyPhen-2 0.00
- SIFT 0.46
- Most common in the Latino/Admixed American population (allele frequency 0.0028)
- Structural context available