W23L (p.Trp23Leu) variant of HLA-B (P01889)
W23L (p.Trp23Leu) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
W23L (p.Trp23Leu) variant details
- p.Trp23Leu
- gnomAD rs1397852593
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.11
- CADD 21.80
- PolyPhen-2 0.99
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.5e-06)
- Structural context available