V52A (p.Val52Ala) variant of HLA-B (P01889)
V52A (p.Val52Ala) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
V52A (p.Val52Ala) variant details
- p.Val52Ala
- gnomAD rs151341109
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.27
- CADD 26.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available