V49E (p.Val49Glu) variant of HLA-B (P01889)
V49E (p.Val49Glu) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
V49E (p.Val49Glu) variant details
- p.Val49Glu
- Ensembl rs41542121
- Missense
- Variant Prioritization Score for Impact Estimate 0.343
- REVEL 0.25
- CADD 24.20
- PolyPhen-2 0.70
- SIFT 0.01
- Most common in the East Asian population (allele frequency 3.7e-05)
- Structural context available