V36L (p.Val36Leu) variant of HLA-B (P01889)
V36L (p.Val36Leu) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
V36L (p.Val36Leu) variant details
- p.Val36Leu
- 1000Genomes rs1050486
- ESP rs1050486
- ExAC rs1050486
- gnomAD rs1050486
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.17
- CADD 18.80
- PolyPhen-2 0.02
- SIFT 0.02
- Most common in the East Asian population (allele frequency 4.2e-05)
- Structural context available