V36A (p.Val36Ala) variant of HLA-B (P01889)
V36A (p.Val36Ala) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
V36A (p.Val36Ala) variant details
- p.Val36Ala
- gnomAD rs137854644
- Missense
- Variant Prioritization Score for Impact Estimate 0.26
- REVEL 0.12
- CADD 22.60
- PolyPhen-2 0.31
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 6.1e-05)
- Structural context available