T22S (p.Thr22Ser) variant of HLA-B (P01889)
T22S (p.Thr22Ser) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
T22S (p.Thr22Ser) variant details
- p.Thr22Ser
- gnomAD rs1297671916
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.19
- CADD 22.60
- PolyPhen-2 0.99
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.5e-06)
- Structural context available