T22P (p.Thr22Pro) variant of HLA-B (P01889)
T22P (p.Thr22Pro) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
T22P (p.Thr22Pro) variant details
- p.Thr22Pro
- gnomAD rs1297671916
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.22
- CADD 23.70
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00022)
- Structural context available