S28P (p.Ser28Pro) variant of HLA-B (P01889)
S28P (p.Ser28Pro) in HLA-B (P01889) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
S28P (p.Ser28Pro) variant details
- p.Ser28Pro
- NCI-TCGA TCGA novel
- gnomAD rs151341090
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- REVEL 0.24
- CADD 28.70
- PolyPhen-2 0.88
- SIFT 0.01
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available