S28F (p.Ser28Phe) variant of HLA-B (P01889)
S28F (p.Ser28Phe) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
S28F (p.Ser28Phe) variant details
- p.Ser28Phe
- 1000Genomes rs41555216
- ESP rs41555216
- ExAC rs41555216
- gnomAD rs41555216
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- REVEL 0.17
- CADD 23.50
- PolyPhen-2 0.09
- SIFT 0.01
- Most common in the Ashkenazi Jewish population (allele frequency 0.00052)
- Structural context available