R45P (p.Arg45Pro) variant of HLA-B (P01889)
R45P (p.Arg45Pro) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
R45P (p.Arg45Pro) variant details
- p.Arg45Pro
- 1000Genomes rs11546719
- ExAC rs11546719
- gnomAD rs11546719
- Missense
- Variant Prioritization Score for Impact Estimate 0.348
- REVEL 0.22
- CADD 22.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 3.1e-05)
- Structural context available