R45L (p.Arg45Leu) variant of HLA-B (P01889)
R45L (p.Arg45Leu) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
R45L (p.Arg45Leu) variant details
- p.Arg45Leu
- 1000Genomes rs11546719
- ExAC rs11546719
- gnomAD rs11546719
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- REVEL 0.15
- CADD 22.60
- PolyPhen-2 1.00
- SIFT 0.02
- Population evidence available
- Structural context available