R45G (p.Arg45Gly) variant of HLA-B (P01889)
R45G (p.Arg45Gly) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
R45G (p.Arg45Gly) variant details
- p.Arg45Gly
- gnomAD rs45509993
- Missense
- Variant Prioritization Score for Impact Estimate 0.28
- REVEL 0.14
- CADD 17.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.3e-06)
- Structural context available