R45C (p.Arg45Cys) variant of HLA-B (P01889)
R45C (p.Arg45Cys) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
R45C (p.Arg45Cys) variant details
- p.Arg45Cys
- gnomAD rs45509993
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.11
- CADD 19.90
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available