R41S (p.Arg41Ser) variant of HLA-B (P01889)
R41S (p.Arg41Ser) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
R41S (p.Arg41Ser) variant details
- p.Arg41Ser
- ExAC rs137854651
- gnomAD rs137854651
- Missense
- Variant Prioritization Score for Impact Estimate 0.295
- REVEL 0.15
- CADD 21.10
- PolyPhen-2 0.04
- SIFT 0.02
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available