R41C (p.Arg41Cys) variant of HLA-B (P01889)
R41C (p.Arg41Cys) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
R41C (p.Arg41Cys) variant details
- p.Arg41Cys
- ExAC rs137854651
- gnomAD rs137854651
- Missense
- Variant Prioritization Score for Impact Estimate 0.301
- REVEL 0.17
- CADD 21.00
- PolyPhen-2 0.02
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.5e-06)
- Structural context available