R38W (p.Arg38Trp) variant of HLA-B (P01889)
R38W (p.Arg38Trp) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
R38W (p.Arg38Trp) variant details
- p.Arg38Trp
- gnomAD rs1338962119
- Missense
- Variant Prioritization Score for Impact Estimate 0.375
- REVEL 0.23
- CADD 28.70
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 0.00018)
- Structural context available