P6L (p.Pro6Leu) variant of HLA-B (P01889)
P6L (p.Pro6Leu) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
P6L (p.Pro6Leu) variant details
- p.Pro6Leu
- 1000Genomes rs765139348
- ExAC rs765139348
- gnomAD rs765139348
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.07
- CADD 22.60
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the 1KG:CEU population (allele frequency 0.0075)
- Structural context available