P6H (p.Pro6His) variant of HLA-B (P01889)
P6H (p.Pro6His) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
P6H (p.Pro6His) variant details
- p.Pro6His
- 1000Genomes rs765139348
- ExAC rs765139348
- gnomAD rs765139348
- Missense
- Variant Prioritization Score for Impact Estimate 0.304
- REVEL 0.12
- CADD 22.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 5.9e-05)
- Structural context available