P44L (p.Pro44Leu) variant of HLA-B (P01889)
P44L (p.Pro44Leu) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
P44L (p.Pro44Leu) variant details
- p.Pro44Leu
- Ensembl rs41564222
- Missense
- Variant Prioritization Score for Impact Estimate 0.367
- REVEL 0.25
- CADD 23.60
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 7.5e-06)
- Structural context available