M4R (p.Met4Arg) variant of HLA-B (P01889)
M4R (p.Met4Arg) in HLA-B (P01889) is a missense change. The available record places it in the context of in allele B*13:02, allele B*15:01, allele B*18:01, allele B*27:01, allele B*27:0. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
M4R (p.Met4Arg) variant details
- p.Met4Arg
- 1000Genomes rs1050458
- ExAC rs1050458
- gnomAD rs1050458
- in allele B*13:02, allele B*15:01, allele B*18:01, allele B*27:01, allele B*27:0
- Missense
- Variant Prioritization Score for Impact Estimate 0.211
- REVEL 0.25
- CADD 14.10
- PolyPhen-2 0.02
- SIFT 0.03
- Population evidence available
- Structural context available