L2V (p.Leu2Val) variant of HLA-B (P01889)
L2V (p.Leu2Val) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
L2V (p.Leu2Val) variant details
- p.Leu2Val
- ExAC rs755208749
- gnomAD rs755208749
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.26
- CADD 4.14
- PolyPhen-2 0.00
- SIFT 0.21
- Population evidence available
- Structural context available