L19P (p.Leu19Pro) variant of HLA-B (P01889)
L19P (p.Leu19Pro) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
L19P (p.Leu19Pro) variant details
- p.Leu19Pro
- ExAC rs41540116
- gnomAD rs41540116
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- REVEL 0.18
- CADD 21.90
- PolyPhen-2 0.01
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 3e-06)
- Structural context available