L17M (p.Leu17Met) variant of HLA-B (P01889)
L17M (p.Leu17Met) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
L17M (p.Leu17Met) variant details
- p.Leu17Met
- 1000Genomes rs1131165
- ESP rs1131165
- ExAC rs1131165
- gnomAD rs1131165
- Missense
- Variant Prioritization Score for Impact Estimate 0.324
- REVEL 0.16
- CADD 23.20
- PolyPhen-2 0.47
- SIFT 0.00
- Most common in the South Asian population (allele frequency 2.9e-05)
- Structural context available