L10I (p.Leu10Ile) variant of HLA-B (P01889)
L10I (p.Leu10Ile) in HLA-B (P01889) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
L10I (p.Leu10Ile) variant details
- p.Leu10Ile
- 1000Genomes rs749523872
- ExAC rs749523872
- gnomAD rs749523872
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.10
- CADD 22.70
- PolyPhen-2 0.30
- SIFT 0.01
- Most common in the 1KG:MSL population (allele frequency 0.018)
- Structural context available